This function builds the contrast matrix
make.contrast(design, condition, contrast = 1)
design | The data.frame which correspond to the pData function of MSnbase |
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condition | xxxxx |
contrast | An integer that Indicates if the test consists of the comparison of each biological condition versus each of the other ones (Contrast=1; for example H0:"C1=C2" vs H1:"C1!=C2", etc.) or each condition versus all others (Contrast=2; e.g. H0:"C1=(C2+C3)/2" vs H1:"C1!=(C2+C3)/2", etc. if there are three conditions). |
A constrat matrix
Thomas Burger, Quentin Giai-Gianetto, Samuel Wieczorek originally in the DAPAR package. Included in this package since DAPAR is to be removed from Bioconductor >= 3.15.
if (FALSE) { utils::data(Exp1_R25_pept, package='DAPARdata') design <- make.design(Biobase::pData(Exp1_R25_pept)) conds <- Biobase::pData(Exp1_R25_pept)$Condition make.contrast(design, conds) }